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目的:探讨蓝光间歇照射辅助三联法(茵栀黄颗粒、妈咪爱、苯巴比妥)治疗小儿黄疸对患儿血清CA199、CRP及载脂蛋白M水平的影响。方法:选取220例我院就诊的黄疸患儿,随机分为研究组和对照组,分别在两组患者治疗前后检测血清CA199、CRP及载脂蛋白M水平。结果:治疗后研究组血清CA199、CRP及载脂蛋白M水平显著性的低于对照组(P<0.05)。结论:蓝光间歇照射辅助三联法对小儿黄疸进行治疗能有效的降低血清CA199、CRP及载脂蛋白M水平。
Objective: To investigate the effects of intermittent irradiation of blue light on triple therapy (Yinzhihuang granule, mommy love, phenobarbital) in children with jaundice on serum CA199, CRP and apolipoprotein M levels. Methods: 220 cases of jaundice in our hospital were randomly divided into study group and control group. Serum CA199, CRP and apolipoprotein M levels were measured before and after treatment in both groups. Results: After treatment, the levels of serum CA199, CRP and apolipoprotein M in the study group were significantly lower than those in the control group (P <0.05). CONCLUSION: Blue-light intermittent irradiation assisted triple therapy can effectively reduce the levels of serum CA199, CRP and apolipoprotein M in children with jaundice.