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目的:研究以钬激光放射状膀胱切开术为核心的综合治疗方法在氯胺酮性膀胱炎治疗中的作用。方法:将26例氯胺酮性膀胱炎患者按收治的时间顺序分为观察组(n=11)和对照组(n=15),对照组采用传统的膀胱水扩张法治疗,观察组采用钬激光放射状膀胱切开术进行治疗。在术前、术后2周、4周和8周分别进行膀胱容量测定、OABSS评分,QOL评分及尿流动力学检查,观察其恢复情况。结果:观察组患者术后膀胱容量较对照组患者术后膀胱容量明显扩大(P<0.05),观察组术后2周,4周及8周OABSS评分,三个观察时间点与对照组比较,差异均有统计学意义(P<0.05)。尿流动力学检查两组患者膀胱收缩力及顺应性无明显异常。结论:钬激光放射状膀胱切开术治疗氯胺酮性膀胱炎安全有效,可以持续改善患者膀胱容量减小及下尿路症状,对于初始膀胱容量>50ml的患者治疗效果良好。
Objective: To investigate the role of holistic laser radial cystectomy in the treatment of ketamine cystitis. Methods: Twenty-six patients with ketocystitis cystitis were divided into observation group (n = 11) and control group (n = 15) according to chronological order of treatment. The control group was treated by traditional bladder water expansion method. The observation group was treated with holmium laser Cystectomy for treatment. The bladder volume, OABSS score, QOL score and urodynamic examination were performed preoperatively, 2 weeks, 4 weeks and 8 weeks after operation respectively to observe the recovery. Results: The volume of bladder in postoperative patients in observation group was significantly higher than that in control group (P <0.05). The OABSS score in observation group at 2 weeks, 4 weeks and 8 weeks after operation was lower than that in control group The differences were statistically significant (P <0.05). Urodynamics examination of the two groups of patients with bladder contractility and compliance no significant abnormalities. Conclusions: Holmium laser radial cystectomy is safe and effective for the treatment of ketamine cystitis, which can improve the bladder capacity and lower urinary tract symptoms continually. The treatment effect is good for patients with initial bladder volume> 50ml.