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本文研究12只家兔硬膜外阻滞局麻药中,添加1:20万肾上腺素(A 组)或0.1%麻黄碱(B 组)对心肌收缩性能影响。结果表明,A 组硬膜外阻滞后血压下降,心输出量(CO)降低,左室收缩峰压(LVSP)和左室内最大上升和下降速率(±do/dt max)不变或有增加;B组能预防阻滞后低血压,CO 增加,LVSP 和±dp/dt max 稍有降低,证实硬膜外腔应用麻黄碱预防低血压,是由于外周血管阻力增加而非心肌收缩性增强的结果。
In this study, 12 rabbit epidural block local anesthetics, the addition of 1: 200000 epinephrine (A group) or 0.1% ephedrine (B group) on myocardial contractility. The results showed that the blood pressure, the cardiac output (CO), the left ventricular systolic pressure (LVSP) and the maximal left ventricular ascending and descending rate (± do / dt max) were unchanged or increased in group A after epidural blockade ; B group can prevent post-block hypotension, increased CO, LVSP and ± dp / dt max decreased slightly, confirmed epidural ephedrine to prevent hypotension, due to increased peripheral vascular resistance rather than increased myocardial contractility result.