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利用在体实验探讨猫体感皮质的神经生物素的染料偶联现象及其细胞的连接方式 ,研究其存在电突触的可能性 ,为内脏伤害性感受神经元间存在神经微环路的推测提供实验资料。在 S 、S 区的内脏大神经代表区 ,用神经生物素标记内脏伤害性感受神经元的同时 ,观察单细胞注射而多重细胞标记即染料偶联现象。在标记成功的 52例中 ,共 1 5例 ( 2 8.8%)出现多种排列方式的神经生物素染色的色素偶联细胞 ,此情况在 S 区更为多见 ( 34.0 %)。提示其间可能存在缝隙连接 ,从而组成交互的环路联系 ,使相关神经元的活动呈现同步化 ,以介导复杂的痛觉反应活动。
To investigate the possibility of electrical synapses using dye-coupled phenomena of neurobiotin in the somatosensory cortex of the cat and its connection with cells in vivo and to provide evidence for the existence of neural microcirculation between visceral nociceptive receptors Experimental data. The visceral nociceptive neurons were labeled with neurobiotin in the visceral large neurons in the S and S regions. Single cell injection and multiple cell labeling, ie, dye coupling, were observed. Among the 52 cases marked successful, 15 cases (2 8.8%) showed a variety of arrangement of neurobiotin-stained dye-coupled cells, which was more common in the S region (34.0%). Suggesting that there may be gap junctions in the meantime, so as to form an interactive loop connection that synchronizes the activities of related neurons to mediate complex pain response activities.