间质性膀胱炎(IC)治疗时,口服给药最多5％～10％到达膀胱。相应地膀胱内灌注治疗的优点是膀胱内药物浓度高,无全药物吸收因而不良反应发生率低,其缺点是间断上导尿管增加病人的负担、发病机率和费用。 Interstitial cystitis (IC) treatment, oral administration of up to 5% to 10% of the bladder. Accordingly, intravesical instillation has the advantage of high drug concentration in the bladder and low incidence of adverse reactions without absorption of the entire drug. The disadvantage is that the intermittent upper urinary catheter increases the patient’s burden, chance of occurrence and cost.