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目的探讨米非司酮在围绝经期功能性子宫出血治疗中的临床效果。方法选取2011年5月~2013年5月间于本院门诊诊治的围绝经期功能性子宫出血患者156例,按其诊治顺序进行编号并随机分为对照组(78例)和观察组(78例),给予对照组患者安宫黄体酮口服治疗,给予观察组患者米非司酮口服治疗,观察两组患者治疗效果、不良反应、复发等指标,并进行统计学对比分析。结果观察组患者治疗有效率100%明显高于对照组患者89.74%,组间差异有统计学意义(P<0.05);观察组患者不良反应发生率6.41%、复发率10.26%均明显低于对照组相应指标17.95%、17.95%,组间差异有统计学意义(P<0.05);结论在功能性子宫出血治疗中,米非司酮可提高患者治疗有效率,减少并发症发生,预防复发,可明显改善患者预后,值得推广。
Objective To investigate the clinical effect of mifepristone in the treatment of functional uterine bleeding during perimenopausal period. Methods 156 cases of peri-menopausal dysfunctional uterine bleeding in our hospital from May 2011 to May 2013 were selected and randomly divided into control group (78 cases) and observation group (78 cases) Cases), given the control group of patients with An oral progesterone progesterone given to patients in the observation group mifepristone oral treatment, the two groups were observed therapeutic effect, adverse reactions, recurrence and other indicators, and statistical analysis. Results The effective rate of treatment in observation group was significantly higher than that in control group (89.74%) (P <0.05). The incidence of adverse reactions in observation group was 6.41% and the recurrence rate was 10.26% (P <0.05) .Conclusion In the treatment of functional uterine bleeding, mifepristone can improve the treatment efficiency, reduce the incidence of complications, prevent recurrence, Can significantly improve the prognosis of patients, it is worth promoting.