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支气管肺发育不良（ BPD）是导致新生儿尤其是早产儿住院时间延长、病死率增加的主要疾病之一，目前无特效治疗方法。目前国内外有关皮质激素预防和治疗BPD的剂量、疗程及不良预后有较多的研究，但研究结果相差甚大，部分结果显示皮质激素可减少 BPD的发生且对远期结局有益处，但部分研究显示其对近期及远期结局不利，不推荐常规使用。今后将进一步研究小剂量地塞米松治疗BPD的效果及其他可替代皮质激素的药物。“,”Bronchopulmonary dysplasia( BPD) is one of the main factors leading to longer hospital stay and higher mortality of neonates especially premature ones ,which has no ideal treatments currently .There are many debates in the prevention and treatment of cortical hormone .Some considered cortical hormone can decrease the incidence of BPD and is beneficial to the long-term outcome,while some found that the short and long term outcome of cortical hormone are bad and should not be recommended for regular usage .In the future,the small dose of hexadecadrol for treatment of BPD and other substituting drugs will be further studied .