论文部分内容阅读
目的研究缺血修饰蛋白在老年急性冠脉综合征患者早期诊断价值。方法选取141例老年均以胸痛为首发症状患者为研究对象,根据肌钙蛋白结果分为两个观察组,分别测量不同时间段的IMA值,同时选取53例健康年龄在60岁以上患者为对照组,测量IMA及CTnI。结果观察组1的IMA值为(125.38±7.49)U/ml,胸痛2组为(96.44±6.96)U/ml。两观察组之间在年龄、性别、吸烟史、血糖等方面差异无统计学意义,而IMA值在两组之间差异有统计学意义(P=0.001)。IMA值用于诊断健康者与老年急性冠脉综合征患者的ROC曲线下面积为0.95,95%可信区间为(0.87、0.96)。结论 IMA可能是老年急性冠脉综合征患者早期诊断指标。
Objective To study the early diagnosis value of ischemia modified protein in elderly patients with acute coronary syndrome. Methods A total of 141 senile patients with chest pain as the first symptom were selected and divided into two observation groups according to the results of troponin. The IMA values of different time periods were measured. At the same time, 53 patients with healthy age over 60 years old were selected as control Group, measure IMA and CTnI. Results The IMA of observation group 1 was (125.38 ± 7.49) U / ml and that of chest pain group 2 was (96.44 ± 6.96) U / ml. There was no significant difference in age, sex, smoking history and blood glucose among the two observation groups, but there was a significant difference in IMA between the two groups (P = 0.001). The area under the ROC curve of IMA values for diagnosing healthy and elderly patients with acute coronary syndrome was 0.95, with a 95% confidence interval (0.87, 0.96). Conclusion IMA may be an early diagnostic indicator of elderly patients with acute coronary syndrome.