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目的了解玉林市人感染猪链球菌病例的临床和流行病学特点,为制定防制措施提供依据。方法对玉林市报告的4例人感染猪链球菌病例进行流行病学个案调查,采集标本检验并送广西区疾病预防控制中心进行复核检测。结果4例病例均为中老年男性,职业为肉制品加工人员或农民,病例散在分布,发病时间为冬春季;传播途径与直接接触猪肉有关,病例手上均有伤口,3例病例无法追溯到可疑猪肉的来源。临床分型均为脑膜脑炎型,病例以发热、畏寒、头晕、头痛、呕吐、昏迷或神志不清、脑膜刺激征阳性、颈项强直、听力减退等症状体征为主,脑脊液呈化脓性改变;4例病例的病原检测结果均为阳性,即猪链球菌特异性基因(16srRNA)、猪链球菌2型荚膜多糖基因(cps2j)阳性。结论人感染猪链球菌病无人传人现象;直接接触猪肉是人感染猪链球菌病的主要途径。
Objective To understand the clinical and epidemiological characteristics of human infection of Streptococcus suis in Yulin City and provide the basis for making prevention and control measures. Methods Four cases of human infection of Streptococcus suis in Yulin City were investigated by epidemiological investigation. Samples were collected and sent to Guangxi Center for Disease Control and Prevention for review. Results The 4 cases were all middle-aged and old men. The occupations were meat processing workers or peasants. The cases were scattered and the onset time was winter and spring. The route of transmission was directly related to pork. All the cases had wounds on hand and 3 cases could not be traced back to The source of suspicious pork. Clinical type were meningoencephalitis type, the cases of fever, chills, dizziness, headache, vomiting, coma or confusion, positive meningeal irritation, neck stiffness, hearing loss and other symptoms and signs of cerebrospinal fluid was purulent changes The pathogenicity test results were positive in all 4 cases, ie, S. suis-specific gene (16srRNA) and Streptococcus suis type 2 capsular polysaccharide gene (cps2j) were positive. Conclusion Human infection with streptococcus suis uninfected phenomenon; direct contact with pork is the main way of human infection with Streptococcus suis.