论文部分内容阅读
目的对医院抗菌药的使用情况及细菌的耐药性进行探讨分析。方法抽查医院近年抗生素的使用情况,并用Excel表对其进行汇总,采用统计方法对其进行了分析。结果医院抗生素的DDDs逐年减少,且β内酰胺酶抑制剂复合制剂、硝基呋喃类、大环内酯类减少量与2013年DDDs所占比例相比差异明显(P<0.05);临床分离的细菌以G-为主,检出率最高的为铜绿假单胞菌、构成比31.2%;鲍曼不动杆菌对大部分抗生素的耐药率均>60%;粪肠球菌仅对万古霉素等少部分抗生素敏感。结论医院抗生素的使用频度与细菌耐药率之间存在相关性。
Objective To investigate the use of antibacterials in hospital and the drug resistance of bacteria. Methods Randomly examining the use of antibiotics in hospitals in recent years and summarizing them with Excel, and using statistical methods to analyze them. Results The DDDs of hospital antibiotics decreased year by year. The decrease of β-lactamase inhibitors, nitrofurans and macrolides was significantly different from that of DDDs in 2013 (P <0.05). The clinical isolates The majority of bacteria were G-positive with the highest detection rate being Pseudomonas aeruginosa, accounting for 31.2%. Acinetobacter baumannii had a resistance rate of> 60% to most antibiotics. Enterococcus faecalis was only resistant to vancomycin A small number of antibiotics and other sensitive. Conclusion There is a correlation between the frequency of hospital antibiotic use and bacterial resistance rate.