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目的 观察 citreoviridin( C I T)对大鼠心脏线粒体的影响。方法 用含 C I T 的毒饲料喂养大鼠1个月,透射电镜观察。结果 实验组动物心肌线粒体出现嵴肿胀,空泡样变,甚至出现肌原纤维溶解现象。结论 C I T 可致大鼠心肌线粒体损伤。
Objective To investigate the effect of citreoviridin (C I T) on mitochondria in rat hearts. Methods Rats fed with toxic diet containing C I T for 1 month were observed by transmission electron microscopy. Results The myocardial mitochondria in the experimental group showed swollen cristae, vacuolar degeneration and even myofibrillar lysis. Conclusion C I T can cause myocardial mitochondrial damage in rats.