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为了阻止脊髓灰质炎的爆发流行,1985年2～3月芬兰组织了一次全国性的三价口服脊髓灰质炎疫苗(OPV)的免疫接种运动。本次研究的健康儿童组,已于1984年11月接种过一剂脊髓灰质炎灭活疫苗(IPV)。作者报道了这部分儿童排毒和抗体应答情况及两者之间的关系。 138份粪便标本中有88份分离出1种或1种以上的脊髓灰质炎病毒株。Ⅲ型病毒除2株外,皆显示类Sabin株抗原特征。106份咽拭子标本中只有1份病毒分离试验阳性。该阳性儿童在4个月前脊髓灰质炎流行期间也
In order to stop the outbreak of poliomyelitis, a national trivalent oral polio vaccine (OPV) immunization campaign was organized in Finland from February to March 1985. The healthy children group of this study was vaccinated with a poliomyelitis inactivated vaccine (IPV) in November 1984. The authors report the detoxification and antibody response in this group of children and their relationship. 88 out of 138 stool samples isolated one or more poliovirus strains. In addition to two strains of type III virus, they all showed Sabin-like antigenic characteristics. Only 1 out of 106 throat swabs tested positive for virus isolation. The positive child also during polio 4 months ago