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一、诊断方面:1.磷酸肌酸激酶同功酶的同形酶:Wever 在70年代发现每种磷酸肌酸激酶同功酶(CPK 同功酶)还有几种亚型。过去研究证明,每种 CPK 同功酶存在于不同的组织中:如骨髂肌内多为 CPK～MM,心肌内多为 CPK—MB,CPK—MM,脑中多为CPK—BB。每种同功酶在色谱上都有一个单独的色谱峰。但如把某一种 CPK 同功酶在体外接种于血清中或注入动物或人体内,这些同功酶就能转变成另一种亚型。在色谱上出现多个色谱峰,这种同功酶的亚型叫异
First, the diagnostic aspects: 1. Phosphocreatine creatine kinase isozyme of the same type: Wever in the 1970s found that each phosphocreatine kinase isoenzyme (CPK isozyme) There are several subtypes. Past studies have shown that each CPK isoenzyme exists in different tissues: such as bone iliac muscle mostly CPK ~ MM, myocardial mostly CPK-MB, CPK-MM, brain mostly CPK-BB. Each isozyme has a single chromatographic peak. However, if a certain CPK isoenzyme in vitro inoculated into the serum or injected into animals or humans, these isozymes can be transformed into another subtype. Multiple chromatographic peaks appear on the chromatogram. The subtype of this isozyme is different