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目的探讨早期应用低分子肝素钙对急性心肌梗死(AMI)患者溶栓疗效的影响。方法选取2012年6月至2014年6月河南省驻马店市汝南县人民医院收治的AMI患者资料98例,按随机数字表法将其分为观察组和对照组,各49例。对照组患者选择在治疗开始后12 h腹部皮下注射低分子肝素,观察组患者于入院后溶栓治疗前30~60 min腹部皮下注射低分子肝素,比较两组患者的冠状动脉再通率和血管再通时间。结果观察组患者的冠状动脉再通率明显高于对照组,再通时间明显短于对照组,差异均有统计学意义(均P>0.05)。结论溶栓治疗前,早期应用低分子肝素治疗可提高AMI患者冠状动脉的再通率,明显缩短血管再通时间。
Objective To investigate the effect of early application of low molecular weight heparin on thrombolysis in patients with acute myocardial infarction (AMI). Methods A total of 98 patients with AMI admitted to Runan County People’s Hospital of Zhumadian City from June 2012 to June 2014 were randomly divided into observation group and control group with 49 cases in each group. In the control group, low molecular weight heparin was injected into the abdomen 12 hours after the start of treatment. The patients in the observation group were given low molecular weight heparin subcutaneously 30 to 60 minutes before admission after thrombolysis. The rates of coronary recanalization and blood vessels Through time. Results In the observation group, the rate of coronary recanalization was significantly higher than that of the control group, and the recanalization time was significantly shorter than that of the control group (all P> 0.05). Conclusion Before thrombolytic therapy, early application of low molecular weight heparin can improve the recanalization rate of coronary artery in patients with AMI and shorten the time of recanalization.