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目的 观察参麦注射液对恶性肿瘤病人在化疗后毒副反应减轻的效果。方法 52例住院肿瘤病人均属中晚期,随机分为二组,均采用经皮穿刺肿瘤供血动脉插管化疗药物灌注,治疗组于介入化疗开始静滴10％参麦注射液80ml+5％葡萄糖500ml,每日1次,连用7～10天1疗程,每月2个疗程。结果 参麦治疗组介入化疗白细胞、血小板降低及恶性呕吐影响与对照组比较P值均小于0.01,介入化疗前后两组体力变化提示参麦组Karnofsky评分明显高于对照组。结论 参麦注射液为中晚期恶性肿瘤介入化疗产生的胃肠功能障碍和骨髓抑制具有明显的预防和减毒作用。
Objective To observe the effect of Shenmai injection on the reduction of toxic side effects in patients with malignant tumor after chemotherapy. Methods 52 cases of inpatients with tumors were middle-late stage and were randomly divided into two groups. All patients were treated with percutaneous puncture tumor infusion catheter chemotherapy drugs. The treatment group began intravenous infusion of 10% Shenmai injection 80ml + 5% glucose in intervention chemotherapy. 500ml once a day, once every 7 to 10 days, 2 courses per month. Results Compared with the control group, the P value of the leukocyte, platelet reduction and malignant vomiting in the interventional chemotherapy of Shenmai treatment group was less than 0.01. The changes in physical strength before and after the intervention chemotherapy indicated that the Karnofsky score of Shenmai group was significantly higher than that of the control group. Conclusion Shenmai injection has obvious preventive and attenuating effects on gastrointestinal dysfunction and myelosuppression caused by interventional chemotherapy in advanced and advanced malignant tumors.