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肺泡麻醉剂分压上升速率儿童比成人快,是否可以部分地用挥发性麻醉剂在血中的溶解度随年龄而增加来解释?本文报道了这方面的实验结果。受试者分为4组:刚分娩的足月新生儿10人,3～7岁儿童11人;20～40岁成人11人;75～85岁老人10人。每人抽血15ml(新生儿从脐静脉,其余从静脉或动脉)。7ml用依地酸抗凝以备查血/气分布系数(BGPC)。8ml取血清查白蛋白、球蛋白、甘油三酸酯和胆固醇浓度。用0.6％异氟醚、0.6％安氟醚、0.6％氟烷和0.05％甲氧氟烷混合气体与抗凝血处理后,同时测这4种麻醉剂的BGPC。
Alveolar anesthetic partial pressure rise rate in children than adults, whether it can be partially used in the blood of the volatile anesthetic solubility increases with age to explain? This article reports the results of this experiment. The subjects were divided into 4 groups: 10 full-term newborns just delivered, 11 children aged 3 to 7, 11 adults aged 20 to 40 and 10 elderly 75 to 85 years old. 15ml of blood per person (newborn from umbilical vein, the rest from the vein or artery). 7ml with edetic acid anticoagulation in preparation for blood / gas distribution coefficient (BGPC). 8ml serum check albumin, globulin, triglyceride and cholesterol concentration. After treatment with 0.6% isoflurane, 0.6% enflurane, 0.6% halothane and 0.05% methoxyflurane and anticoagulant, the BGPCs of the four anesthetics were measured simultaneously.