摘要目的研究在单皮质下梗死进展过程中临床、实验室、超声和成像参数之间的联系。方法连续招募169例大脑中动脉(MCA)供血区梗死而大脑中动脉无狭窄的病人进行脑卒中进展过程的研究,分为腔隙性梗死组(89例)和纹状体内囊梗死组(80例)。用经颅超声多普勒测量同侧M1的动脉搏动指数(PI)。结果纹状体内囊梗死组伴脑卒中表现者更多。进展期的腔隙性梗死病人多伴有糖尿病、糖化血红蛋白水平偏高及美国国立卫生研究院脑卒中量表(NIHSS)评分 Abstract Objective To study the relationship between clinical, laboratory, ultrasound and imaging parameters during the progression of subcortical infarction. Methods A total of 169 patients with infarction of the middle cerebral artery (MCA) and no stenosis of the middle cerebral artery were enrolled in the study. They were divided into lacunar infarction group (89 cases) and striatum group (80 cases) example). The arterial pulse index (PI) of ipsilateral M1 was measured by transcranial Doppler. Results There were more cases of striatal internal infarction with stroke. Patients with advanced lacunar infarcts are often associated with diabetes, elevated levels of HbA1c and NIHSS score