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目的:探讨术中注射纳米碳混悬液在甲状腺乳头状癌中央区淋巴清扫手术中的临床价值。方法:回顾性分析270例甲状腺乳头状癌连续病例的临床和病理资料,其中70例(78侧)术中注射纳米碳混悬液(观察组),200例(215侧)未注射(对照组),所有标本行病理检查。结果:两组患者基本临床病理资料无统计学差异(均P>0.05),具有可比性;观察组和对照组检出淋巴结总数分别为475枚和790枚,观察组平均每侧检出淋巴结数多于对照组(5.50vs.3.00,P<0.01),但两组间合并淋巴细胞甲状腺炎患者检出淋巴结数差异无统计学意义(6.00vs.4.50,P>0.05);观察组染色淋巴结转移率低于未染色淋巴结(21.67%vs.39.15%,χ2=17.250,P<0.01)。结论:纳米碳可增加甲状腺乳头状癌手术中央区淋巴结检出数量,但对于合并淋巴细胞甲状腺炎患者可能作用有限。
Objective: To investigate the clinical value of intraoperative injection of nanocarbon suspension in lymph node dissection in central papillary thyroid carcinoma. Methods: The clinical and pathological data of 270 consecutive cases of thyroid papillary carcinoma were retrospectively analyzed. Among them, 70 cases (78 sides) were injected with nano-carbon suspension (observation group), 200 cases (215 sides) were not injected ), All specimens underwent pathological examination. Results: There was no significant difference in the basic clinical pathological data between the two groups (all P> 0.05). The total number of lymph nodes in the observation group and the control group were 475 and 790, respectively. The average number of lymph nodes (5.50 vs.3.00, P <0.01). However, there was no significant difference in the number of lymph nodes detected between the two groups (6.00 vs 4.50, P> 0.05). The staining lymph node metastasis Rate was lower than that of unstained lymph nodes (21.67% vs.39.15%, χ2 = 17.250, P <0.01). Conclusion: Nano-carbon can increase the number of lymph nodes in central papillary thyroid carcinoma surgery, but may have limited effect on patients with lymphocytic thyroiditis.