目的了解我院门诊、急诊不合理使用抗菌药物情况,促进临床合理用药。方法采用回顾性调查方法,随机抽取我院2010年度1～12月份门诊、急诊处方21600张,对抗菌药物不合理的处方进行分析。结果 21600张处方中有8210张使用了抗菌药物,抗菌药物用药不合理处方748张,主要表现在无指征用药、给药方案不合理、同类抗菌药联用、选用溶媒不合理、药理拮抗、选药不合理等方面。结论我院存在一定程度的抗菌药物不合理使用,应引起重视,临床医师要提高自己的合理用药水平,同时药师也应加强监管。 Objective To understand the outpatient clinic, irrational use of antibiotics in emergency situations, to promote clinical rational use of drugs. Methods A retrospective survey method was used to randomly select 21600 outpatient and emergency prescriptions in our hospital from January to December in 2010 to analyze the unreasonable antibacterial prescriptions. Results Among the 21,600 prescriptions, 8,210 antibacterials were used and 748 irrational antibacterials were prescribed. The main indications were that there were no indications, unreasonable dosage regimens, combinations of similar antibacterials, unreasonable selection of solvents, antagonism of pharmacology, Drugs unreasonable and so on. Conclusion There is a certain degree of irrational use of antimicrobial agents in our hospital, which should be paid more attention to. Clinicians should improve their rational drug use level and at the same time pharmacists should also strengthen their supervision.