论文部分内容阅读
目的研究二氢杨梅素及其衍生物对SP2/0小鼠骨髓瘤细胞增殖的抑制率。方法采用MTT法检测细胞的增殖。结果二氢杨梅素、二氢杨梅素-3-没食子酸酯对SP2/0小鼠骨髓瘤细胞的生长具有显著抑制作用;二氢杨梅素全酯及其醚的抑制作用较低。结论二氢杨梅素及其衍生物对SP2/0小鼠骨髓瘤细胞增殖抑制作用与其抗氧活性具有一定相关性。
Objective To study the inhibitory effect of dihydromyricetin and its derivatives on the proliferation of SP2 / 0 mouse myeloma cells. Methods Cell proliferation was detected by MTT assay. RESULTS: Dihydromyricetin and dihydromyricetin-3-gallate had a significant inhibitory effect on the growth of SP2 / 0 mouse myeloma cells. The inhibitory effect of dihydromyricetin and its ether was low. Conclusions Dihydromyricetin and its derivatives have some effects on the anti-proliferation activity of SP2 / 0 mouse myeloma cells.