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1924年就有人发现卟啉在动物及人的恶性肿瘤中聚集,并在光照后发生特异荧光。1960年Lipsoa研制从血卟啉衍生物(HPD)。1973年起Dougherty和早田义博等进行了大量基础理论研究工作。随着激
In 1924, it was discovered that porphyrins accumulated in animal and human malignancies and that they exhibited specific fluorescence after light irradiation. In 1960 Lipsoa was developed from the hematoporphyrin derivative (HPD). Since 1973, Dougherty and Okada Yoshihiro have conducted a lot of basic theoretical research. With the stimulus