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本文对43例原发性高血压住院患者的24小时尿激肽排泄量进行测定,并同63例正常健康者进行比较。前者24小时排泄量为19.2±10.7微克,后者为24.2±11.7微克,前者似低于后者,但统计处理未达显著水平(P>0.05)。与Lieberthal等报道黑人的情况相似。原发性高血压患者的24小时尿激肽排泄量与血尿素氮、血钙、血钾、尿钠及尿钾排泄量或血压水平都无明显关联;与PRA、血ATⅡ及尿醛固酮排泄量也无显著相关,与国外有些报道不一致,原因何在,有待进一步研究阐明。
In this paper, 43 patients with essential hypertension inpatients 24 hours urinary kinin excretion was measured and compared with 63 normal healthy subjects. The former 24 hours excretion was 19.2 ± 10.7 micrograms, the latter 24.2 ± 11.7 micrograms, the former seems lower than the latter, but the statistical treatment was not significantly (P> 0.05). Similar to the case of blacks reported by Lieberthal et al. There was no significant correlation between urinary excretion of 24-hour urinary kinin in patients with essential hypertension and blood urea nitrogen, serum calcium, serum potassium, urinary sodium and urinary potassium excretion or blood pressure; with PRA, blood ATⅡ and urinary aldosterone excretion There is no significant correlation with some reports of foreign inconsistencies, the reason why, pending further study to clarify.