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目的:回顾总结非穿透性小梁切除联合透明质酸钠生物胶植入及丝裂霉素应用治疗开角型青光眼的疗效。方法:对20例24眼开角型青光眼施行非穿透性小梁切除手术,术中巩膜床植入透明质酸生物胶及应用丝裂霉素,术后随访12～36mo,观察眼压、视力、前房角、滤过泡等情况。结果:术后1,2,3a时眼压分别为16.32±5.25,17.28±5.70,18.26±5.20mmHg,与术前眼压35.52±7.6mmHg相比明显下降(P<0.01)。术后视力达到或高于术前水平22眼,视力下降2眼。术中、术后均未出现浅前房及前房炎症反应。24眼均有功能型滤过泡。结论:非穿透性小梁切除联合透明质酸钠生物胶植入及丝裂霉素应用能安全、有效地治疗开角型青光眼。
OBJECTIVE: To review the curative effect of non-penetrating trabecular surgery combined with sodium hyaluronate implantation and mitomycin treatment for open-angle glaucoma. Methods: Twenty patients (24 eyes) with open-angle glaucoma underwent non-penetrating trabecular surgery. The scleral bed was implanted with hyaluronic acid bio-gel and mitomycin C during operation. The patients were followed up for 12 to 36 months. The intraocular pressure Eyesight, anterior chamber angle, filtered bleb and so on. Results: The intraocular pressure at 1, 2 and 3 months after operation were 16.32 ± 5.25, 17.28 ± 5.70 and 18.26 ± 5.20mmHg, respectively, which was significantly lower than preoperative intraocular pressure 35.52 ± 7.6mmHg (P <0.01). Postoperative visual acuity reached or higher than the preoperative level of 22 eyes, visual acuity decreased 2 eyes. No intraoperative, postoperative anterior chamber and anterior chamber inflammation. 24 eyes had a functional filtering bleb. Conclusion: Non-penetrating trabeculectomy combined with sodium hyaluronate bio-implants and mitomycin can safely and effectively treat open-angle glaucoma.