患者,男,65岁。3年前发现左侧腹股沟区皮肤瘙痒,可见米粒样丘疹,破溃后有黄色液体流出,皮肤呈橘皮样改变,长期按皮炎治疗,无效,半年前症状加重,出现表浅溃疡,渗液,并向周边扩大,病检报告:乳腺外Paget病。体检发现左侧腹股沟区约4cm×3cm大小区域皮肤橘皮样变,可见局部小溃疡形 Patient, male, 65 years old. 3 years ago found the left groin area pruritus, visible rice-like papules, rupture of yellow liquid outflow, the skin was orange-like changes, long-term dermatitis treatment, invalid, symptoms increased six months ago, superficial ulcers, exudate , And to the periphery to expand, disease inspection report: Extramammary Paget disease. Physical examination found about 4cm × 3cm area of ​​the left groin area of ​​the skin orange peel-like changes, showing small local ulcer-shaped