肝癌的基因治疗研究发展非常迅速,自杀基因疗法是其中之一。病毒或细菌中的一些酶可将无毒或低毒的药物前体转化为致死性的毒性化合物。自杀基因疗法即将编码这些酶的基因导入到靶细胞中,因此也称为“病毒介导的酶/前体药物疗法”(virus-directed Gene therapy for hepatocellular carcinoma is developing rapidly and suicide gene therapy is one of them. Some enzymes in viruses or bacteria can convert non-toxic or low-toxic prodrugs to lethal toxic compounds. Suicide gene therapy involves the introduction of genes encoding these enzymes into target cells and is therefore also known as “virus-directed” (virus-directed