儿童多发性硬化(MS)罕见,不足全部病例的0.5％。由于其症状不典型和病程不稳定,造成诊断上的困难。迄今能帮助临床诊断的实验室技术有限。脑CT对多数病例无助益,尤其是早期病例和症状轻微者。核磁共振影像(NMR)对成人MS敏感,并已成为极为重要的诊断手段。但用于诊断儿童的MS尚无报道。作者报道3例临床和实验室已证实为MS的儿童,其NMR显示了典型的有诊断意义的显著的改变。 Children with multiple sclerosis (MS) rare, less than 0.5% of all cases. Due to its atypical symptoms and course of instability, causing diagnostic difficulties. Laboratory technology that has so far helped to diagnose clinics is limited. Most cases of brain CT without benefit, especially in early cases and mild symptoms. Magnetic resonance imaging (NMR) is sensitive to adult MS and has become an extremely important diagnostic tool. However, no MS has been reported for the diagnosis of children. The authors report that in 3 children with clinical and laboratory proven MS, their NMR showed a significant, clinically significant change.