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结核分枝杆菌作为最重要的传染性病原体之一,其引起的结核病已经成为全球性的社会公共卫生问题。结核分枝杆菌耐药性的发生,是引起结核病治疗失败以及结核病患者死亡的重要危险因素。耐多药结核病(MDR-TB)的出现和流行是造成结核病疫情回升的主要原因之一,并且对于结核病的控制形成了障碍。随着全球范围内对于MDR-TB的日益重视,各种预防和治疗MDR-TB的新观点和新方法不断被提出。现就近年来MDR-TB控制策略方面的研究进展予以综述。
Mycobacterium tuberculosis, one of the most important infectious pathogens, causes tuberculosis has become a global social and public health problem. Mycobacterium tuberculosis drug resistance is caused by the failure of tuberculosis treatment and death of tuberculosis is an important risk factor. The emergence and prevalence of multidrug-resistant tuberculosis (MDR-TB) are one of the major causes of the rebound of TB epidemics, and they constitute an obstacle to the control of tuberculosis. With the growing global emphasis on MDR-TB, new ideas and new approaches to prevent and treat MDR-TB continue to be proposed. The research progress of MDR-TB control strategy in recent years is reviewed.