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以小鼠腹腔巨噬细胞吞噬功能测定,羊红细胞致敏测定小鼠血清溶血素含量,探讨了叶下珠复方制剂肝丹对免疫功能的影响。结果表明:肝丹大剂量组吞噬百分率、吞噬指数、半数溶血值显著优于空白对照组,与阳性对照组左旋咪唑相似。提示肝丹具有调节小鼠的免疫机制、提高免疫能力的作用,并呈量效正相关。
The phagocytic function of mouse peritoneal macrophages was measured. Sheep red blood cell sensitization was used to determine the serum hemolysin content in mice. The effect of Gan Xidan, a compound preparation of Ye Xiazhu, on immune function was investigated. The results showed that the percentage of phagocytosis, phagocytic index and half hemolysis of the high-dose Gandan group were significantly better than those of the blank control group, and similar to that of the positive control group. It is suggested that Gandan has the function of regulating the immune mechanism of mice and improving the immunity, and it is positively related to the dose effect.