甲状腺乳头状癌淋巴结转移相关因素分析

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目的探讨甲状腺乳头状癌颈淋巴结转移的相关因素。方法收集2005年1月—2008年3月接受手术并进行淋巴结切除的38例(44侧)甲状腺乳头状癌患者的临床资料(不包含因复发手术的病例),回顾分析甲状腺乳头状癌淋巴结转移的相关因素。结果在38例(44侧)患者中,颈淋巴结的转移率为57.89%,颈部中央区淋巴结转移(47.37%)为最常见的转移部位,出现颈侧区淋巴结转移的患者(31.58%)中66.67%同时伴有中央区淋巴结转移。颈部淋巴结转移的相关因素为年龄<45岁和肿瘤侵犯被膜,多因素分析显示,年龄为淋巴结转移的独立相关因素。结论颈淋巴结转移是甲状腺乳头状癌的常见情况,尤其是中央区淋巴结;建议有甲状腺被膜侵犯的甲状腺乳头状癌患者应常规清扫中央区淋巴结。 Objective To investigate the related factors of cervical lymph node metastasis in papillary thyroid carcinoma. Methods The clinical data of 38 patients (44 sides) with papillary thyroid carcinoma who underwent surgery and lymph node dissection from January 2005 to March 2008 were collected. Excluding the cases of recurrent thyroid papillary carcinoma, the retrospective analysis of lymph node metastasis of papillary thyroid carcinoma Related factors. Results In 38 patients (44 sides), the metastasis rate of cervical lymph nodes was 57.89%. The most common metastatic lymph nodes in the cervical region (47.37%) were metastatic lymph nodes in the cervical region (31.58%) 66.67% accompanied by central lymph node metastasis. The related factors of cervical lymph node metastasis were age <45 years and tumor invasion of the capsule. Multivariate analysis showed that age was an independent factor related to lymph node metastasis. Conclusion Cervical lymph node metastasis is a common thyroid papillary carcinoma, especially in the central lymph nodes; thyroid papillary thyroidectomy is recommended in patients with thyroid capsule should be routine dissection of the central lymph nodes.
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