现在认为原发性进行性虹膜萎缩、Chandler综合征和虹膜-痣综合征这三者均属于“增生性内皮综合征”的范畴,通常称为角膜虹膜内皮综合征(ICE综合征)。该病为单眼发病,无家族性,主要见于女性白人。其共同特点为:(1)虹膜基质异常,包括瞳孔异位、虹膜变薄及孔洞形成;(2)虹膜附着于Schwalbe线或其前部广泛的虹膜周边前粘连;(3)青光眼;(4)角膜后部改变。Shields等发现在本 Now consider primary progressive iris atrophy, Chandler syndrome, and iris-nevus syndrome, all three of which fall into the category of “proliferative endothelium syndrome,” commonly referred to as corneal iris endothelium syndrome (ICE syndrome). The disease is monocular disease, no familial, mainly seen in female whites. The common features are: (1) iris matrix abnormalities, including the pupillary ectopic, iris thinning and the formation of holes; (2) the iris attached to the Schwalbe line or its anterior wide iris adhesion; (3) glaucoma; (4) Corneal posterior changes. Shields et al found in this