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患儿,男,30天,因全身皮肤黄染18天入院。自发病来,精神食欲好,无发热,大便稀,每天7～8次,有时恶心、呕吐。查体:体温37.4℃,发育正常,营养差,皮肤、巩膜明显黄染,心肺未见异常,肝肋下3cm,剑下2cm,质韧,脾肋下1.5cm。实验室检查:白细胞8200,中性粒细胞55％,血红蛋白11g,血小板104000。黄疸指数96U,凡登白直接迅速反应(++++),谷丙转氨酶200U,血培养有埃希氏大肠杆菌生长。诊断为大肠杆菌败血症。入院后予庆大霉素、氨苄青霉素地塞米松1～3mg/kg.d,以及输血治疗。病情不好转,大便次数增多,腹胀明显,入院后22天,白细胞降至3600,中性粒细胞88％,血红蛋白6g,
Children, male, 30 days, due to systemic skin yellow dye 18 days admission. Since onset, good appetite, no fever, loose stools, 7 to 8 times a day, and sometimes nausea and vomiting. Physical examination: body temperature 37.4 ℃, normal development, poor nutrition, skin, sclera obvious yellow dye, no abnormal heart and lungs, liver ribs 3cm, sword 2cm, quality toughness, spleen rib 1.5cm. Laboratory tests: white blood cells 8200, 55% of neutrophils, hemoglobin 11g, 104000 platelets. Jaundice index 96U, Vandenbai direct response (++++), alanine aminotransferase 200U, blood culture with Escherichia coli growth. Diagnosed as E. coli sepsis. After admission to gentamicin, ampicillin dexamethasone 1 ~ 3mg / kg.d, and transfusion therapy. Condition did not improve, stool frequency increased, abdominal distension significantly, 22 days after admission, leukopenia 3600, 88% of neutrophils, hemoglobin 6g,