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目的评价天津市实施甲型肝炎(甲肝)免疫策略后控制甲肝的效果。方法分析天津1990—2006年甲肝疫情资料,评价疫情报告系统,估算甲肝疫苗目标人群接种率,对比1999年和2005年15岁以下健康人群甲肝抗体水平。结果天津市甲肝发病率从1990年的25.26/10万降到2006年的0.82/10万,甲肝在病毒性肝炎中的比例从1990年的30.43%降到2006年的1.05%;估算全市目标人群甲肝疫苗接种率平均为72.7%;2005年15岁以下人群甲肝抗体阳性率达到61.84%,明显高于1999年的29.90%。结论天津市5年甲肝疫苗免疫策略的实践成功控制了甲肝流行。
Objective To evaluate the effect of controlling hepatitis A after implementing Hepatitis A (Hepatitis A) immunization strategy in Tianjin. Methods The data of Hepatitis A in Tianjin from 1990 to 2006 were analyzed, the epidemic reporting system was evaluated, the vaccination rate of target population of Hepatitis A vaccine was estimated, and the antibody level of Hepatitis A in healthy population below 15 years old in 1999 and 2005 was compared. Results The incidence of hepatitis A in Tianjin dropped from 25.26 / 100000 in 1990 to 0.82 / 100000 in 2006. The proportion of hepatitis A in viral hepatitis dropped from 30.43% in 1990 to 1.05% in 2006. The target population of the whole city The average vaccination rate of hepatitis A vaccine was 72.7%. In 2005, the positive rate of hepatitis A antibody in people below 15 years old reached 61.84%, significantly higher than 29.90% in 1999. Conclusion The practice of 5-year hepatitis A vaccine immunization strategy in Tianjin has successfully controlled the spread of hepatitis A virus.