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对复合真菌多糖作为保健食品的抑癌作用进行评价，并初步研究其作用机制。［方法］选用小鼠Ｓ_(１８０)肉瘤及Ｌｅｗｉｓ肺癌移植性肿瘤模型，以《保健食品功能学评价程序和检验方法》为实验依据。［结果］复合真菌多糖０．３３ ｇ／ｋｇ、１．００ ｇ／ｋｇ剂量组对小鼠移植性Ｓ_(１８０)肉瘤及Ｌｅｗｉｓ肺癌抑制率两次均达到３０％以上．复合真菌多糖０． ３３ ｇ／ｋｇ组可显著增加小鼠腹腔巨噬细胞吞噬鸡红细胞的吞噬率，１． ００ ｇ／ｋｇ组对小鼠 ＮＫ细胞活性也有明显增强作用人［结论］复合真菌多糖对小鼠 Ｓ_(１８０)肉瘤及 Ｌｅｗｉｓ肺癌有明显的抑癌效应，其机制可能与调节机体的免疫功能，提高机体的免疫监视作用有关。
The anti-cancer effect of the compound fungal polysaccharide as a health food was evaluated and its mechanism of action was preliminary studied. [Methods] The mouse S_(180) sarcoma and Lewis lung cancer transplanted tumor models were selected, and the experiment was based on the “Health Food Functional Evaluation Procedure and Test Method”. [Results] The inhibition rates of transplanted S 180 sarcoma and Lewis lung cancer in the compound fungal polysaccharides 0.33 g/kg and 1.00 g/kg were both above 30%. Compound Fungal Polysaccharides 33 g/kg group can significantly increase the phagocytic rate of phagocytic chicken phagocytic macrophages to engulf chicken erythrocytes. The effect of 00 g/kg group on the activity of NK cells in mice was also significantly enhanced. [Conclusion] The compound fungal polysaccharides have a significant tumor suppressor effect on S180 sarcoma and Lewis lung cancer, and its mechanism may be related to the regulation of immune function. Improve the immune surveillance function of the body.