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目的 探讨脑卒中后癫痫的临床特点及发病机制。方法 对 2 1 0 0例脑卒中病例中 1 92例继发癫痫的临床资料进行回顾性分析。结果 卒中后癫痫的发生率为 9.1 %。早期癫痫发作 6.0 4 % ,晚期癫痫发作 3 .0 9% ,卒中后癫痫的发生率与病灶部位 (皮质 /皮质下 )差异有显著性 (P<0 .0 1 ) ,与卒中类型差异不明显 (P>0 .0 5)。结论 脑水肿是早期癫痫发作的重要致痫因素 ,晚期发作癫痫是因胶质疤痕等因素形成癫痫灶所致。建议对晚期发作癫痫进行严格系统的有效治疗。
Objective To investigate the clinical features and pathogenesis of post-stroke epilepsy. Methods The clinical data of 1 92 secondary epilepsy cases among 210 cases of stroke were retrospectively analyzed. Results The incidence of post-stroke epilepsy was 9.1%. The incidence of epileptic seizures was 6.04% in early seizures and 3.90% in advanced seizures. The incidence of epilepsy after stroke was significantly different from that of the lesion (cortical / subcortical) (P <0.01), but not significantly different from the type of stroke (P> 0.05). Conclusion Cerebral edema is an important cause of epileptic seizures in early epilepsy. Late seizures are caused by factors such as glial scarring and epilepsy. It is recommended that patients with advanced seizures be strictly and systematically treated effectively.