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本文系消化道平滑肌肿瘤(ASMT)病理研究的第一篇,常规病理观察936例。计有食管198例、胃354例、小肠243例、大肠141例。通过病理观察发现平滑肌瘤(LM)与平滑肌肉瘤(LS)数目相等,各为468例。LS 又分为Ⅰ、Ⅱ、Ⅲ级。LM 及 LS 中共有上皮样 SMT 分化者29例。根据观察结果,建议恶性指标为:瘤细胞核分裂数≥2/25高倍视野(HPF);瘤细胞形态有一定异形;有中等以上的细胞致密度;肿瘤侵犯周围组织;瘤体大径≥6cm;肿瘸伴坏死及囊性变。
This article is the first part of the pathological study of digestive tract smooth muscle tumor (ASMT), routine pathological observation of 936 cases. There were 198 cases of esophagus, 354 cases of stomach, 243 cases of small intestine, and 141 cases of large intestine. By pathological observation, the number of leiomyosarcoma (LM) and leiomyosarcoma (LS) was equal to 468 cases. LS is divided into I, II, III levels. There were 29 cases of epithelioid SMT differentiation in LM and LS. According to the observation results, it is recommended that the malignant index is: the number of tumor nuclear fibroids ≥ 2/25 high power field (HPF); the shape of the tumor cells has a certain shape; the density of cells with a medium or more degree; the tumor invades the surrounding tissue; the diameter of the tumor body is ≥ 6cm; Tumors with necrosis and cystic degeneration.