口腔粘膜上的中毒性皮肤病通常为红斑型和水泡型,类似于多形红斑征候群或复发固定着色性红斑症候群,与发生于口腔内的溃疡着色增殖型药物疹亦非常相似。通过四个病例报告,作者描述本病的临床特征为口腔疼痛性发疹,浸润性口疮样溃疡,预先不出现小疱,溃疡较小(小于1厘米),稍圆,中央为灰黄色坏死区,周围有红斑性晕。这四个病例的情况是:例一为48岁的女性患者,自子宫摘除术后采用苯(艹印)二酮治疗,于术后二周出现上述口腔疹伴皮肤疖疮,停 Oral mucosa of the toxic skin disease is usually erythema and blister type, similar to polymorphous erythema syndrome or recurrent fixed colored erythema syndrome, and occurred in the oral ulcer coloring drug rash is also very similar. Through four case reports, the authors describe the clinical features of the disease as oral pain eruptions, infiltrative aphthous ulcers, no prior small blisters, ulcers smaller (less than 1 cm), slightly rounded, central grayish necrotic area , Around the erythema of the halo. In these four cases, the first case was a 48-year-old woman who had been treated with benzene (diprin) dione after a hysterectomy and who developed the oral rash with cutaneous scabies two weeks after surgery