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目的了解伴间质特殊分化的子宫Ｍｕｌｌｅｒｉａｎ腺肉瘤的临床病理特征及其鉴别诊断。方法收集７例间质形态特殊的子宫腺肉瘤，观察其临床病理特点，并进行组织化学及免疫组化染色分析。结果所有肿瘤具有腺肉瘤的临床及组织学特征，２例问质出现组织学形态和免疫组化特点均与恶性横纹肌样瘤相似的区域，１例伴性索样成分，３例伴横纹肌肉瘤及１例伴灶性软骨成分。结论腺肉瘤间质可向横纹肌样分化，可能与间质细胞的多分化潜能密切相关。这７例伴间质特殊分化的腺肉瘤的临床及病理特点与典型的腺肉瘤基本一致。
Objective To understand the clinicopathological features and differential diagnosis of Mullerian adenosarcoma with interstitial special differentiation. Methods Seven cases of uterine adenosarcoma with interstitial morphology were collected. The clinicopathological features were observed and analyzed by histochemistry and immunohistochemistry. Results All the tumors had the clinical and histological features of adenosarcoma. There were two cases with histological features and immunohistochemical features similar to those of malignant rhabdomyosarcoma. One case had a cord-like component and three had rhabdomyosarcoma 1 case with focal cartilage composition. Conclusions The adenosquamous stroma can differentiate into striated muscle, which may be closely related to the multipotentiality of stromal cells. The clinical and pathological features of 7 cases of adenosarcoma with special stromal differentiation were basically the same as those of typical adenosarcoma.