目的探讨９９ｍＴｃ甲氧基异丁基异腈（ＭＩＢＩ）脑显像对脑肿瘤的诊断价值。方法对８例正常对照者和３１例脑肿瘤患者分别行９９ｍＴｃＭＩＢＩ脑血流显像和断层显像。脑血流显像观察病变部位血液供应情况；断层显像分别于注射后１５～３０分钟（早期相）和２～３小时（延迟相）进行，观察病变部位摄取９９ｍＴｃＭＩＢＩ的情况，并在横断面或冠状面图像上，分别计算早期相和延迟相肿瘤部位（Ｔ）与对侧（Ｃ）和脉络丛（ＣＰ）单位象素的放射性计数比值（Ｔ／Ｃ和Ｔ／ＣＰ），进行半定量分析。结果血流显像脑肿瘤组１２例异常。断层显像所有受检者早期相和晚期相均可见ＣＰ部位放射性浓集，正常对照组脑实质内无放射性浓集；脑肿瘤组２０例显像阳性，肿瘤部位放射性异常浓集，Ｔ／Ｃ及Ｔ／ＣＰ较对照组高。９９ｍＴｃＭＩＢＩ检出脑肿瘤的灵敏度和特异性分别为６４５％和１００％。结论９９ｍＴｃＭＩＢＩ脑显像对诊断脑肿瘤有一定的临床意义 Objective To investigate the diagnostic value of 99mTc-methoxyisobutylisonitrile (MIBI) brain imaging in brain tumors. Methods 8 cases of normal controls and 31 cases of brain tumor patients were 99mTcMIBI cerebral blood flow imaging and imaging. Cerebral blood flow imaging was used to observe the blood supply of the lesion. Tomographic imaging was performed at 15 to 30 minutes (early phase) and 2 to 3 hours (delayed phase) respectively after injection, and the 99mTcMIBI uptake was observed. Radionuclide ratios (T / C and T / CP) for the early and delayed tumor sites (T) and the contralateral (C) and choroid plexus (CP) units of pixels were calculated on a cross-sectional or coronal image, respectively, Semi-quantitative analysis. Results Blood flow imaging brain tumor group 12 cases were abnormal. Tissue imaging showed that there was no radioactive concentration in the brain parenchyma in all the subjects at early phase and late phase, and no radioactive concentration in brain parenchyma in normal control group. Tumor imaging showed positive in 20 cases and abnormal radioactivity in T / C And T / CP higher than the control group. The sensitivity and specificity of 99mTcMIBI in detecting brain tumors were 645% and 100% respectively. Conclusion 99mTc MIBI brain imaging for the diagnosis of brain tumors have some clinical significance