论文部分内容阅读
树突状细胞(Dendritic Cell,DC)是目前发现的功能最强的专职性抗原递呈细胞(APC),能摄取和加工递呈抗原,具有强大的激活CD8+、CTL及CD4+T辅助细胞的能力,控制着体内免疫反应的过程,在免疫应答中处于中心地位,因而成为肿瘤免疫反应的中心环节。DC可以在体外培养后用于体内免疫治疗,也可辅以细胞因子或其它因子如Flt-3等在体内扩增[1]。DC包括:朗罕氏细胞、间质树突细胞、并指状树突细胞等。人DC缺乏B细胞、
Dendritic cells (DCs) are currently the most potent and specialized antigen-presenting cells (APCs) that can take up and process antigen presentation and have strong activation of CD8 +, CTL and CD4 + T helper cells Ability to control the process of immune response in the immune response at a central position, which became the center of the immune response of the tumor. DC can be used for in vivo immunotherapy after being cultured in vitro, and also can be expanded in vivo by supplementing with cytokines or other factors such as Flt-3 [1]. DCs include: Langerhans cells, interstitial dendritic cells, and finger dendritic cells. Human DCs lack B cells,