本文以刑事司法协助为基点,探讨了中国内地与港澳刑事司法协助的性质。在此基础上,进一步阐述了中国内地与港澳刑事司法协助的国家主权统一原则,分析适用该原则的“一国两制”基础及一些不适用规则。这是内地与港澳共同打击互涉刑事案件、实现“一国两制三法域”基础上有中国特色的区际刑事司法协助的首要原则。 This article explores the nature of criminal justice assistance between the Mainland of China and Hong Kong and Maucao on the base of criminal justice assistance. On this basis, we further elaborate on the principle of national sovereignty reunification of the criminal justice between Mainland China and Hong Kong and Maucao, and analyze the “one country, two systems” basis and some non-applicable rules applying this principle. This is the first principle that the Mainland and Hong Kong and Macao jointly crack down on criminal cases of interdiction and realize “inter-regional criminal justice assistance with Chinese characteristics” based on “one country, two systems and three jurisdictions.”