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目的:探讨血液透析(HD)联合血液灌注(HP)治疗尿毒症患者的临床疗效。方法:维持性透析患者30例,15例采用血液透析(HD)联合血液灌注(HP)治疗,为联合组。15例只采用血液透析治疗,为对照组。对两组治疗后的血清肌酐(SCr)、β2微球蛋白(β2-MG)、甲状旁腺激素(PTH)、尿素氮(BUN)含量及症状缓解情况进行比较。结果:联合组治疗前后SCr、β2-MG、PTH、BUN都显著降低,差异具有统计学意义(P<0.05),且症状缓解较好。对照组改善不明显。结论:血液透析联合血液灌注对尿毒症的治疗比较有优势。
Objective: To investigate the clinical effect of hemodialysis (HD) combined with hemoperfusion (HP) on patients with uremia. Methods: Thirty patients were divided into maintenance hemodialysis patients and 15 patients were treated with hemodialysis (HD) combined with hemoperfusion (HP). 15 cases were treated with hemodialysis only, as the control group. Serum creatinine (SCr), β2 microglobulin (β2-MG), parathyroid hormone (PTH), blood urea nitrogen (BUN) levels and symptom relief were compared between the two groups after treatment. Results: The levels of SCr, β2-MG, PTH and BUN in the combined group were significantly decreased before and after treatment (P <0.05), and the symptoms were relieved. The control group did not improve obviously. Conclusion: Hemodialysis combined with blood perfusion has advantages in the treatment of uremia.