辅助生殖技术(ART)被誉为20世纪改变人类生活的重大科技发明之一。经过30余年的飞速发展,妊娠率已经相对稳定,周期平均成功率已达到40%。发达国家通过ART出生的婴儿占出生婴儿总数的1%甚至更多。随着ART的普及,其安全性引起了广泛的关注。自1978年7月25日世界上首例试管婴儿Louis Brown在英国诞生后,人类ART在世界范围内广泛 Assisted reproductive technology (ART) is known as one of the major scientific and technological inventions that changed human life in the 20th century. After more than 30 years of rapid development, the pregnancy rate has been relatively stable, with an average cycle success rate of 40%. Infants born in ART in developed countries account for 1% or more of the total number of babies born. With the popularity of ART, its safety has caused widespread concern. Since the birth of the world’s first IVF baby Louis Brown in the UK on July 25, 1978, human ART has become widespread in the world