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报告过氧化氢对家兔脑影响的实验研究，以及对人脑影响的临床发现。接触过氧化氢家兔脑组织中的自由基ESR检测信号，丙二醇含量，水份含量，出血水肿的组织学改变和抽搐症状均较对照组明显增高（P＜0．001）。临床病例发现一例开放性脑损伤因创口应用过氧化氢溶液冲洗导致病人抽搐、昏迷和持续植物状态。一例慢性硬膜下血肿因术中应用过氧化氢溶液冲洗导致术后出血、水肿、半球损害症状和脑萎缩改变。一例高血压外囊脑出血因术中应用过氧化氢溶液冲洗导致脑水肿昏迷和死亡。故认为过氧化氢对正常脑组织是非常有害的。
Experimental study of the effects of hydrogen peroxide on the brain of rabbits and clinical findings on the human brain. Free radical ESR signal, propylene glycol content, water content, histological changes of hemorrhage and edema and twitch symptom in rabbits exposed to hydrogen peroxide were significantly higher than those in control group (P <0.001). One case of clinical brain injury was found to cause convulsions, coma and persistent vegetative state in a patient with open brain injury due to wound application of hydrogen peroxide solution. A case of chronic subdural hematoma due to the application of hydrogen peroxide solution rinse resulted in postoperative bleeding, edema, hemisphere damage symptoms and brain atrophy changes. A case of hypertensive cystocele due to intraoperative application of hydrogen peroxide solution flushing lead to cerebral edema coma and death. Therefore, hydrogen peroxide on normal brain tissue is very harmful.