女患,25岁。因恶心、呕吐伴腹痛、腹泻2天。当地医生诊断为“急性胃肠炎”。给予静脉滴注10％葡萄糖500ml+卡那霉素1.5/g。当液体进入约150ml时,患者突然胸闷,呼吸急促,抽搐。继之意识不清。立即停止静脉滴注。肌注非那根25mg,45分钟后送往我院。既往有青霉素过敏史。体查:体温36.8℃。呼吸36次/分。血压、脉搏测不到。面色苍白,深昏迷状态。心音低纯,心率116次/分,四肢冰冷。入院时诊断为:卡那霉素致过 Female, 25 years old. Due to nausea, vomiting with abdominal pain, diarrhea 2 days. Local doctor diagnosed as “acute gastroenteritis.” Give intravenous infusion of 10% glucose 500ml + kanamycin 1.5 / g. When the liquid into about 150ml, the patient suddenly chest tightness, shortness of breath, convulsions. Followed by unconsciousness. Stop intravenously immediately. Intramuscular injection of non-root 25mg, 45 minutes later sent to our hospital. Past history of penicillin allergy. Physical examination: body temperature 36.8 ℃. Breath 36 beats / min. Blood pressure, pulse can not be measured. Pale, deep coma. Low heart sound, heart rate 116 beats / min, limbs cold. Admission is diagnosed as: kanamycin induced