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关于痢疾杆菌对豚鼠眼结膜,角膜引起实验性感染,国外学者已先后证明,如1924年法国Zoellerche和Manousakis,匈牙利Seriny氏,以及最近苏联学者(1957),H.A.等(1959)。这一实验可以识别痢疾杆菌与非痢疾杆菌。他们的实验结果均指出,凡是新分离出的痢疾杆菌接种豚鼠眼结膜均能在24小时内引起豚鼠的眼结膜炎;而实验室保存的痢疾菌株和其他肠系杆菌,如伤寒、副伤寒杆菌,大肠杆菌,变形杆菌,若接种于豚鼠眼结膜,并不能引起与痢疾杆菌相似的病变。国内冯振南、方纲等氏于1958年对此也进行了实验研究。但这些文献的报导,均着重在感染方法、发病现象以及由于感染而引起的免疫性意义等方面的探讨。有关痢疾杆菌豚鼠眼结膜试验的临床应用这一方面的文献尚
About dysentery bacilli conjunctival guinea pig conjunctiva, cornea caused by experimental infection, foreign scholars have successively proved, such as 1924 French Zoellerche and Manousakis, Hungarian Seriny’s, and the recent Soviet scholar (1957), H.A. (1959). This experiment can identify Shigella dysenteriae and non-Shigella. Their experimental results all pointed out that any newly isolated dysentery bacillus inoculated guinea pig conjunctiva can cause guinea pig conjunctivitis within 24 hours; and laboratory-preserved dysentery strains and other Enterobacteriaceae such as typhoid, paratyphoid bacilli , E. coli, Proteus, if inoculated guinea pig conjunctiva, and can not cause similar diseases and Shigella. Feng Zhennan, Fang Gang et al in 1958 also conducted an experimental study of this. However, the reports of these literatures are all focused on the methods of infection, the pathogenesis and the immunological significance caused by infection. The literature on the clinical application of dysentery bacilli guinea pig conjunctiva test is still