论文部分内容阅读
目的探讨CA153,CA125,CEA在乳腺癌诊断中的应用和临床价值。方法对450例患者行CA153,A125,CEA检查,其中正常体检对照者40例,乳腺良性增生患者286例,乳腺癌患者124例。结果 CA1 5 3,CA1 2 5,CEA的检测结果从正常对照者到乳腺癌患者之间呈逐渐增高的趋势,3组间差异均有统计学意义(P<0.0 5)。CA1 5 3,CA1 2 5,CEA检测乳腺癌的特异度均较高。CEA在有无淋巴结转移的乳腺癌患者中检测值差异有统计学意义。结论 CA153,CA125,CEA的联合检测对于乳腺癌的诊断和鉴别诊断具有一定的价值,但仍需寻找更有价值的乳腺肿瘤标志物。
Objective To investigate the application and clinical value of CA153, CA125 and CEA in the diagnosis of breast cancer. Methods A total of 450 patients were examined with CA153, A125 and CEA. Among them, 40 were normal physical examination controls, 286 were benign breast hyperplasia, and 124 were breast cancer patients. Results The results of CA1 5 3, CA 1 2 5 and CEA showed a gradually increasing trend from normal controls to breast cancer patients. The differences among the three groups were statistically significant (P < 0.05). The specificity of CA1 5 3, CA 1 2 5, CEA in detecting breast cancer was high. There was a statistically significant difference in the detection of CEA in breast cancer patients with or without lymph node metastasis. Conclusion The combined detection of CA153, CA125 and CEA is of value in the diagnosis and differential diagnosis of breast cancer, but it is still necessary to find more valuable breast tumor markers.