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目的:探讨口服锌制剂对治疗小儿急性腹泻的临床疗效。方法:将148例急性腹泻患儿随机分为观察组和对照组,每组各74例,两组患儿均予以常规治疗,观察组在此基础上加用锌制剂口服,观察两组患者的临床疗效。结果:观察组患儿治疗总有效率为95.9%,显著高于对照组的77.0%,观察组平均止泻时间为(2.35±1.02)d,对照组平均止泻时间为(4.48±2.83)d,两组患儿总有效率和平均止泻时间之间的差异有统计学意义(P<0.05),两组患儿治疗后均未发现不良反应。结论:在常规治疗基础上加用口服葡萄糖酸锌治疗小儿急性腹泻临床疗效好,平均止泻时间少,且方便安全,不良反应发生率较低,值得临床进一步推广使用。
Objective: To investigate the clinical efficacy of oral zinc preparations in the treatment of children with acute diarrhea. Methods: 148 children with acute diarrhea were randomly divided into observation group and control group, with 74 cases in each group. Both groups were given routine treatment. On the basis of this, oral zinc was added to the observation group, Clinical efficacy. Results: The total effective rate of observation group was 95.9%, which was significantly higher than that of control group (77.0%). The average antidiarrheal time in observation group was (2.35 ± 1.02) d and that in control group was (4.48 ± 2.83) d There was a significant difference between the two groups in the total effective rate and the average time of antidiarrheal (P <0.05). No adverse reaction was found in both groups after treatment. Conclusion: The combination of oral zinc gluconate and oral zinc gluconate in the treatment of children with acute diarrhea has good curative effect, less average diarrhea time, convenient and safe, and lower incidence of adverse reactions. It is worth further promotion in clinic.