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麻风病人使用联合化疗的目的在于:缩短疗期,增加病人就诊,防止 DDS 耐药,增强疗效和减少工作量。作者在少菌型麻风中应用联合化疗并评价其疗效。研究对象为129例少菌型病人(TT95,BT19,I15),其中40人有局部神经粗大和触痛。病人服DDS100mg/日,利福平600mg/月(监服)。对经此方案治疗6个月临床仍活动的病人,继续给予治疗与随访6月以上。经联合化疗一年临床仍活动的25例作组织病理检查。临床已无活动性的病人则解除医疗监督,但继续随访、停止治疗。
The purpose of leprosy combined chemotherapy is to shorten the treatment period, increase patient visits, prevent DDS drug resistance, enhance efficacy and reduce workload. The authors apply combination chemotherapy in minimal bacteria leprosy and evaluate its efficacy. The object of study was 129 patients with minimal bacilli (TT95, BT19, I15), 40 of whom had local nerve enlargement and tenderness. Patient service DDS100mg / day, rifampicin 600mg / month (supervisor). On this program for 6 months after treatment of patients still active clinical treatment and follow-up more than 6 months. After a year of combined chemotherapy in the clinical activity of 25 cases for histopathological examination. Patients with clinically inactive patients lifted their medical supervision, but continued follow-up and discontinued treatment.