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目的:探讨十二指肠间质瘤的临床症状和诊治方法。方法:回顾性分析32例十二指肠胃肠间质瘤患者的病例资料。结果:32例病例中,7例高危,7例低危,13例中危,5例极低危。治疗手段采用外科手术,其中8例十二指肠节段切除,5例胰十二指肠切除,其中合并右半结肠切除2例,肿瘤局部切除16例,其中1例合并胃大部远端切除。术后随访10～36个月,3例因肿瘤复发或转移而死亡,29例获得完整随访,无肿瘤生存。结论:十二指肠胃肠间质瘤的术前诊断方法仍然以内镜检查和CT最为有效,确诊则依靠病理及免疫组化。而治疗手段仍然以外科手术治疗为主要方法,但手术方案应该根据肿瘤的大小和部位谨慎选择。
Objective: To investigate the clinical symptoms, diagnosis and treatment of duodenal stromal tumors. Methods: Retrospective analysis of 32 cases of patients with duodenal gastrointestinal stromal tumors. Results: Of the 32 cases, 7 were high risk, 7 were low risk, 13 were moderately dangerous, and 5 were extremely low risk. Surgical treatment was used, including 8 cases of duodenal resection and 5 cases of pancreatoduodenectomy, including 2 cases of right hemicolectomy, 16 cases of local tumor resection, 1 case of distal part of the stomach combined resection. After 10 to 36 months of follow-up, 3 patients died due to tumor recurrence or metastasis. 29 patients were followed up completely without tumor survival. CONCLUSIONS: Preoperative diagnostic methods for duodenal gastrointestinal stromal tumors are still most effective with endoscopy and CT. The diagnosis depends on pathology and immunohistochemistry. The treatment is still the main method of surgical treatment, but the surgical program should be carefully selected according to the size and location of the tumor.