肝癌是世界上最常见的恶性肿瘤之一,且肝癌的预后很差。肝癌发生的分子机制仍有待进一步研究。20世纪90年代末出现的组织芯片技术为医学分子生物学提供了一种高通量、大样本及快速的分子水平的分析工具。本文就组织芯片技术及其在肝癌中的应用作一简要综述。1组织芯片的概念及 Liver cancer is one of the most common malignancies in the world, and the prognosis of liver cancer is poor. The molecular mechanism of liver cancer still needs further study. The tissue chip technology that emerged in the late 1990s provides a high-throughput, large-sample, and rapid molecular-level analysis tool for medical molecular biology. This article gives a brief review of tissue chip technology and its application in liver cancer. 1 The concept of organizational chips and